The importance of vitamin d metabolism as a potential prophylactic, immunoregulatory and neuroprotective treatment for COVID-19. Moo IH, Kam CJW, Cher EWL, Peh BCJ, Lo CE, Chua DTC, Lo NN, Howe TS, Koh JSB.

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Neurosteroid hormone vitamin D and its utility in clinical nutrition. Based on these assumptions, we have written this review to summarize the potential role of vitamin D in neurological pathologies.

NLM DeLuca GC, Kimball SM, Kolasinski J, Ramagopalan SV, Ebers GC. Vitamin D system comprises hormone precursors, active metabolites, carriers, enzymes, and receptors involved in genomic and non-genomic effects.

Nat. The vitamin D hormone and its nuclear receptor: molecular actions and disease states. 2008;87:1080S–1086S. The authors declare no conflict of interest.  |  J. Mol.

Archivio Istituzionale della Ricerca Unimi, Norman A.W. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. AD; MS; VDH; VDR; calcium; demyelination; neuro-degeneration; stroke; vascular disease; vitamin D-OH 25. Int. With vitamin D deficiency reaching epidemic proportions worldwide, there is now concern that optimal levels of vitamin D in the bloodstream are also necessary to preserve the neurological development and protect the adult brain. -. J. Clin. Epub 2015 Jul 23. 2020 Jun 10;12(6):1743. doi: 10.3390/nu12061743. A bibliographical search was performed in the MedLine and Cochrane library databases. Vuolo L, Di Somma C, Faggiano A, Colao A.

Studies confirm that for bariatric surgery patients, neurological disorders are primarily the result of vitamin/mineral deficiencies, 2 and immediate diagnosis and prompt treatment are critical for preventing long-term, irreversible damage. Chouët J, Sacco G, Karras SN, Llewellyn DJ, Sánchez-Rodríguez D, Annweiler C. Front Neurol.

J Cardiovasc Pharmacol Ther. Metab. Agarwal M, Phan A, Willix R Jr, Barber M, Schwarz ER. Barrea L, Muscogiuri G, Laudisio D, Pugliese G, de Alteriis G, Colao A, Savastano S. Nutrients.

Homann CN, Ivanic G, Homann B, Purkart TU. 2020 Sep 18;11:1034. doi: 10.3389/fneur.2020.01034. We have explored the relationships between the gene-environmental influence and long-term vitamin D deficiency, as a risk factor for the development of different types of neurological disorders, along with the role and the rationale of therapeutic trials with vitamin D implementation. This site needs JavaScript to work properly. Neuroscience. Immunomodulatory Effects of Vitamin D in Thyroid Diseases.

1998;67:1108–1110. Please enable it to take advantage of the complete set of features!

The aim of this review is to highlight the relationship between vitamin D and neurological diseases.

FASEB J. Vitamin D and Delirium in Older Adults: A Case-Control Study in Geriatric Acute Care Unit. USA.gov. Epub 2008 May 13. These fast-dissolving tablets contain a high concentration of vitamin B12 to bypass normal absorptive mechanisms that rely on intrinsic factor. Specific actions on the central nervous system (CNS) have been described.

Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Conclusions: 2020 Sep 11;12(9):2788. doi: 10.3390/nu12092788.

In older adults, hypovitaminosis D has been associated with neuromuscular disorders, dementia, and Parkinson's disease. Crit Care Med. Sultan S, Taimuri U, Basnan SA, Ai-Orabi WK, Awadallah A, Almowald F, Hazazi A. J Aging Res.

Multidisciplinary Digital Publishing Institute (MDPI). 2011 Apr;39(4):885-6. doi: 10.1097/CCM.0b013e318208e5c2.

eCollection 2020. Mutua AM, Mogire RM, Elliott AM, Williams TN, Webb EL, Abubakar A, Atkinson SH. Adv Biomed Res. BMC Musculoskelet Disord. Please enable it to take advantage of the complete set of features! Holick M.F.

One of these mechanisms is through neuronal apoptosis. Vitamin D has been shown to have multiple biological targets mediated by the vitamin D receptor present in many cells. The studies published over the past 20 years provide an increasing number of arguments in favor of a life-long role of vitamin D on the nervous system as a whole, and in particular on the CNS.

COVID-19 is an emerging, rapidly evolving situation. -, Prentice A., Schoenmakers I., Jones K., Jarjou L.A., Goldberg G. Vitamin D Deficiency and Its Health Consequences in Africa. This work could be titanic and the results might have been very fuzzy and even incoherent had we not conjectured to taper our first intentions and devoted our interests towards three mainstreams, demyelinating pathologies, vascular syndromes, and neurodegeneration. Endocrinol. eCollection 2020. Considering taking a vitamin or supplement to treat Neurological-Trauma? In older adults, hypovitaminosis D has been associated with neuromuscular disorders, dementia, and Parkinson's disease. The keywords used were: 'vitamin D' and 'nervous system' and/or 'central nervous system' and/or 'nervous system diseases' and/or 'psychological tests' and/or 'neuropsychological tests' and/or 'mental disorders'. Genome Res.

There are several proposed mechanisms by which hypovitaminosis D may impact these disorders.

2008 Oct;28(5):343-9, 384; quiz 350.

Metab.

Acta Neurol Scand Suppl. 2012 Apr 23;3:58. doi: 10.3389/fendo.2012.00058. 2020 Jul 27;9:32. doi: 10.4103/abr.abr_188_19. Wellcome Open Res. Neuroscience.

doi: 10.1038/nrendo.2010.146. Epub 2011 Feb 8.  | 

NIH Get the latest research from NIH: https://www.nih.gov/coronavirus. Schematic overview of neurological disorders and their underlying mechanisms relating to impaired homeostasis of the vitamin D system. Vitamin D and neurological disorders Hypovitaminosis D is associated with several neuropsychiatric disorders including dementia, Parkinson's disease, multiple sclerosis, epilepsy, and schizophrenia. HHS As a result of the lack of useful therapeutic options, apart from the disease-modifying strategies, the role of different risk factors should be investigated in neurology, as their correction may lead to the improvement of the cerebral conditions. Moreover, vitamin D deficiency has been associated with neurological and psychiatric disorders. Vitamin D regulation of GDNF/Ret signaling in dopaminergic neurons. doi: 10.1186/gb-2010-11-5-206.

doi: 10.1016/bs.afnr.2015.11.001. J. Med. Please enable it to take advantage of the complete set of features!

In addition to classical bone-related effects, this system has also been shown to activate multiple molecular mediators and elicit many physiological functions. 2018 Feb;32(2):819-828. doi: 10.1096/fj.201700713R. 2020 Aug 8;21(1):524. doi: 10.1186/s12891-020-03554-1. NIH Vitamin d deficiency: A worldwide problem with health consequences. Epub 2018 Jan 4.

Cobalamin enters the body with animal products. eCollection 2020. Mele C, Caputo M, Bisceglia A, Samà MT, Zavattaro M, Aimaretti G, Pagano L, Prodam F, Marzullo P. Nutrients. Horm Metab Res.

-, Holick M.F., Chen T.C. 2016 Nov;73(6):1427-1431. The term "vitamin B12 (cobalamin)" refers to several substances (cobalamins) of a very similar structure. Vitamin D deficiency as a potential risk factor for accelerated aging, impaired hippocampal neurogenesis and cognitive decline: a role for Wnt/β-catenin signaling. Dietary Intake of Vitamin D from Dairy Products Reduces the Risk of Osteoporosis.



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